Bob Hoskins
Eddie Valiant
Christopher Lloyd
Judge Doom
Joanna Cassidy
Dolores
Charles Fleischer
Roger Rabbit / Benny The Cab / Greasy / Psycho (voice)
Kathleen Turner
Jessica Rabbit (voice) (uncredited)
Stubby Kaye
Marvin Acme
Alan Tilvern
R.K. Maroon
Richard LeParmentier
Lt. Santino
Lou Hirsch
Baby Herman (voice)
Betsy Brantley
Jessica's Performance Model
